So far, we've explored three interlinked causes of insulin resistance: cellular energy excess, inflammation, and insulin resistance in the brain. In this post, I'll explore the effects on micronutrient status on insulin sensitivity.
Micronutrient Status
There is a large body of literature on the effects of nutrient intake/status on insulin action, and it's not my field, so I don't intend this to be a comprehensive post. My intention is simply to demonstrate that it's important, and highlight a few major factors I'm aware of.
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Monday, January 9, 2012
Sunday, January 8, 2012
New Year
Happy New Year friends!
It is hard to believe we are 8 days into the year 2012. I am considering tomorrow my first day of the New Year seeing as last week was a wash with no school until Tuesday, re-entry a little harsh, and a case of the holiday blues...as in for the first time in the last couple of years I was sad to see my children go back to school, husband to work, because we were having such a nice time together. Now it is alarm clocks, schedules, meetings, and packing lunches. I do a lot of running around town, so much in fact I sometimes make myself car sick with my own driving...hmm.
Something I need to work on this year, slowing it down a bit, finding balance, and peace within. I have to wonder what this year will bring? With all the attention over the weekend surrounding Catherine the Duchess of Cambridge's 30th birthday tomorrow it just goes to show you exactly what can happen in one person's life over the course of a year.
We will see, I already have a few little princes that have my heart and I like to think of myself as the queen of the house so what will be next...
What Causes Insulin Resistance? Part III
As discussed in previous posts, cellular energy excess and inflammation are two important and interlinked causes of insulin resistance. Continuing our exploration of insulin resistance, let's turn our attention to the brain.
The brain influences every tissue in the body, in many instances managing tissue processes to react to changing environmental or internal conditions. It is intimately involved in insulin signaling in various tissues, for example by:
Read more »
The brain influences every tissue in the body, in many instances managing tissue processes to react to changing environmental or internal conditions. It is intimately involved in insulin signaling in various tissues, for example by:
- regulating insulin secretion by the pancreas (1)
- regulating glucose absorption by tissues in response to insulin (2)
- regulating the suppression of glucose production by the liver in response to insulin (3)
- regulating the trafficking of fatty acids in and out of fat cells in response to insulin (4, 5)
Read more »
Saturday, January 7, 2012
What Causes Insulin Resistance? Part II
In the last post, I described how cellular energy excess causes insulin resistance, and how this is triggered by whole-body energy imbalance. In this post, I'll describe another major cause of insulin resistance: inflammation.
Inflammation
In 1876, a German physician named W Ebstein reported that high doses of sodium salicylate could totally eliminate the signs and symptoms of diabetes in certain patients (Berliner Klinische Wochenschrift. 13:337. 1876). Following up on this work in 1901, the British physician RT Williamson reported that treating diabetic patients with sodium salicylate caused a striking decrease in the amount of glucose contained in the patients' urine, also indicating an apparent improvement in diabetes (2). This effect was essentially forgotten until 1957, when it was rediscovered.
Read more »
Inflammation
In 1876, a German physician named W Ebstein reported that high doses of sodium salicylate could totally eliminate the signs and symptoms of diabetes in certain patients (Berliner Klinische Wochenschrift. 13:337. 1876). Following up on this work in 1901, the British physician RT Williamson reported that treating diabetic patients with sodium salicylate caused a striking decrease in the amount of glucose contained in the patients' urine, also indicating an apparent improvement in diabetes (2). This effect was essentially forgotten until 1957, when it was rediscovered.
Read more »
Friday, January 6, 2012
What Causes Insulin Resistance? Part I
Insulin is an ancient hormone that influences many processes in the body. Its main role is to manage circulating concentrations of nutrients (principally glucose and fatty acids, the body's two main fuels), keeping them within a fairly narrow range*. It does this by encouraging the transport of nutrients into cells from the circulation, and discouraging the export of nutrients out of storage sites, in response to an increase in circulating nutrients (glucose or fatty acids). It therefore operates a negative feedback loop that constrains circulating nutrient concentrations. It also has many other functions that are tissue-specific.
Insulin resistance is a state in which cells lose sensitivity to the effects of insulin, eventually leading to a diminished ability to control circulating nutrients (glucose and fatty acids). It is a major contributor to diabetes risk, and probably a contributor to the risk of cardiovascular disease, certain cancers and a number of other disorders.
Why is it important to manage the concentration of circulating nutrients to keep them within a narrow range? The answer to that question is the crux of this post.
Read more »
Insulin resistance is a state in which cells lose sensitivity to the effects of insulin, eventually leading to a diminished ability to control circulating nutrients (glucose and fatty acids). It is a major contributor to diabetes risk, and probably a contributor to the risk of cardiovascular disease, certain cancers and a number of other disorders.
Why is it important to manage the concentration of circulating nutrients to keep them within a narrow range? The answer to that question is the crux of this post.
Read more »
Wednesday, January 4, 2012
New York Times Magazine Article on Obesity
For those of you who haven't seen it, Tara Parker-Pope write a nice article on obesity in the latest issue of NY Times Magazine (1). She discusses research showing that the body "resists" fat loss attempts, making it difficult to lose fat and maintain fat loss once obesity is established.
Read more »
Read more »
Monday, January 2, 2012
High-Fat Diets, Obesity and Brain Damage
Many of you have probably heard the news this week:
High-fat diet may damage the brain
Eating a high-fat diet may rapidly injure brain cells
High fat diet injures the brain
Brain injury from high-fat foods
Your brain cells are exploding with every bite of butter! Just kidding. The study in question is titled "Obesity is Associated with Hypothalamic Injury in Rodents and Humans", by Dr. Josh Thaler and colleagues, with my mentor Dr. Mike Schwartz as senior author (1). We collaborated with the labs of Drs. Tamas Horvath and Matthias Tschop. I'm fourth author on the paper, so let me explain what we found and why it's important.
The Questions
Among the many questions that interest obesity researchers, two stand out:
The Findings
Read more »
High-fat diet may damage the brain
Eating a high-fat diet may rapidly injure brain cells
High fat diet injures the brain
Brain injury from high-fat foods
Your brain cells are exploding with every bite of butter! Just kidding. The study in question is titled "Obesity is Associated with Hypothalamic Injury in Rodents and Humans", by Dr. Josh Thaler and colleagues, with my mentor Dr. Mike Schwartz as senior author (1). We collaborated with the labs of Drs. Tamas Horvath and Matthias Tschop. I'm fourth author on the paper, so let me explain what we found and why it's important.
The Questions
Among the many questions that interest obesity researchers, two stand out:
- What causes obesity?
- Once obesity is established, why is it so difficult to treat?
The Findings
Read more »
Sunday, January 1, 2012
Junk Free January
Last year, Matt Lentzner organized a project called Gluten Free January, in which 546 people from around the world gave up gluten for one month. The results were striking: a surprisingly large proportion of participants lost weight, experienced improved energy, better digestion and other benefits (1, 2). This January, Lentzner organized a similar project called Junk Free January. Participants can choose between four different diet styles:
If you've been waiting for an excuse to improve your diet, why not join Junk Free January?
- Gluten free
- Seed oil free (soybean, sunflower, corn oil, etc.)
- Sugar free
- Gluten, seed oil and sugar free
If you've been waiting for an excuse to improve your diet, why not join Junk Free January?
Friday, December 30, 2011
A Touch of Rose
"You either have a flair, or you haven't"
Rose Cummings
Rose Cummings, Unknown, Caroline Robert, Marc Jacobs, and Windsor Smith
Sunday, December 25, 2011
Popular short Asian bob hairstyles - 2012 Short Asian Bob Hairstyles
Popular short Asian bob hairstyles - 2012 Short Asian Bob Hairstyles
The short haircut is very popular in the last 2 years, and still hot this year, especially in Asian, just like Japan, Korea. Today we will update some popular short Asian bob hairstyles, hope you love it.
A messy short curly bob haircut with brown, black color.
2012 Short Korean bob haircut with bangs, this is a good short hairstyle for heavy hair.
This is really a cute short bob hairstyle for Asian girls. A cute Korean girl with sleek short bob haircut.
A Japanese girl with medium short bob hair. The weaves and bangs are popular in Asian.
2012 short haircut: Another wavy bob haircut with blunt bangs.
short hairstyles 2012: A trendy short bob haircut for Asian girls.
2012 Asian bob hairstyles for girls: Another wavy bob haircut
Short Japanese bob hairstyle 2012: layered short cut with bangs.
Asian bob haircut 2012: A Japanese girl with short center parted bob haircut.
A cute short Japanese bob hairstyle for girls.
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The short haircut is very popular in the last 2 years, and still hot this year, especially in Asian, just like Japan, Korea. Today we will update some popular short Asian bob hairstyles, hope you love it.
A messy short curly bob haircut with brown, black color.
2012 Short Korean bob haircut with bangs, this is a good short hairstyle for heavy hair.
A Japanese girl with medium short bob hair. The weaves and bangs are popular in Asian.
Asian bob haircut 2012: A Japanese girl with short center parted bob haircut.
A cute short Japanese bob hairstyle for girls.
Saturday, December 24, 2011
Latest women hairstyles 2012 - 2012 Hair Trends: Popular Hairstyles 2012
Latest women hairstyles 2012 - 2012 Hair Trends: Popular Hairstyles 2012
Short Medium Long hairstyles 2012
you want to achieve a new look in the coming year, then you will definitely want to consider a new hairstyle. With just a simple change to cut and color, you can have a whole new look that can be trendy, fashionable and modern. To get a hairstyle that you will love, you will want to know what options you have. The best thing to do would be to consider the popular hairstyles of 2012. You just might find a style that you will love. Here are some options that you could consider.
The Short Haircuts 2012
Right now, popular hairstyles of 2012 trend largely toward short styles. This is most likely because so many celebrities are choosing these short styles. We all know that celebrities are certainly the trendsetters when it comes to style! The short looks that are popular hairstyles of 2012 include everything from a dramatic extremely short pixie cut to a more classic layered bob.
Some of the popular styles to consider would be to take your cue from celebs like Keira Knightly and Emma Watson who are sporting a super short pixie cut. If you want something a little longer, consider the choppy layers that celebs like Kristin Cavallari are choosing.
The Medium length hair styles 2012
If you prefer something a little longer, then there are plenty of popular hairstyles in 2012 of medium length. For something modern, consider a shoulder sweeping bob. If the hair is cut in choppy ends, the look can be quite modern. Shoulder length curls are also popular for the coming year. If you choose a medium length style, make sure you use the right products to keep it modern and sophisticated. Pomades can be quite handy in creating straight, choppy looks. A volumizing spray can be useful to add height.
The Long hairstyles 2012
Some of the most popular hairstyles of 2012 are also quite long. Again, this would have to do with celebrity looks. Many celebrities like Blake Lively and Jennifer Lopez are making these styles trendy. To keep the long strands from looking boring, the trend now is to include lots of texture. Beachy waves are especially popular and can be achieved through a texturizing spray that includes sugar or sea salt.
For a more defined long look, new hairstyles of 2012 also include sleek, choppy layers and sideswept bangs. To get the smooth, sleek look, you will need to make use of a quality flat iron and a straightening spray. Be careful that the hair does not get flat since popular styles now include plenty of body at the roots.
Searching Tags for 2012 Hair Trends:- Medium length hair styles 2012, Latest women hairstyles 2012, 2012 Hairstyle Trends, Popular Hairstyles 2012, top ten Hairstyles 2012, best women hairstyles 2012, Long hairstyles 2012, Medium length hair styles 2012, women hairstyle pictures, latest women haircut, Latest female hairstyles 2012
Short Medium Long hairstyles 2012
you want to achieve a new look in the coming year, then you will definitely want to consider a new hairstyle. With just a simple change to cut and color, you can have a whole new look that can be trendy, fashionable and modern. To get a hairstyle that you will love, you will want to know what options you have. The best thing to do would be to consider the popular hairstyles of 2012. You just might find a style that you will love. Here are some options that you could consider.
The Short Haircuts 2012
Right now, popular hairstyles of 2012 trend largely toward short styles. This is most likely because so many celebrities are choosing these short styles. We all know that celebrities are certainly the trendsetters when it comes to style! The short looks that are popular hairstyles of 2012 include everything from a dramatic extremely short pixie cut to a more classic layered bob.
Some of the popular styles to consider would be to take your cue from celebs like Keira Knightly and Emma Watson who are sporting a super short pixie cut. If you want something a little longer, consider the choppy layers that celebs like Kristin Cavallari are choosing.
The Medium length hair styles 2012
If you prefer something a little longer, then there are plenty of popular hairstyles in 2012 of medium length. For something modern, consider a shoulder sweeping bob. If the hair is cut in choppy ends, the look can be quite modern. Shoulder length curls are also popular for the coming year. If you choose a medium length style, make sure you use the right products to keep it modern and sophisticated. Pomades can be quite handy in creating straight, choppy looks. A volumizing spray can be useful to add height.
The Long hairstyles 2012
Some of the most popular hairstyles of 2012 are also quite long. Again, this would have to do with celebrity looks. Many celebrities like Blake Lively and Jennifer Lopez are making these styles trendy. To keep the long strands from looking boring, the trend now is to include lots of texture. Beachy waves are especially popular and can be achieved through a texturizing spray that includes sugar or sea salt.
For a more defined long look, new hairstyles of 2012 also include sleek, choppy layers and sideswept bangs. To get the smooth, sleek look, you will need to make use of a quality flat iron and a straightening spray. Be careful that the hair does not get flat since popular styles now include plenty of body at the roots.
Searching Tags for 2012 Hair Trends:- Medium length hair styles 2012, Latest women hairstyles 2012, 2012 Hairstyle Trends, Popular Hairstyles 2012, top ten Hairstyles 2012, best women hairstyles 2012, Long hairstyles 2012, Medium length hair styles 2012, women hairstyle pictures, latest women haircut, Latest female hairstyles 2012
Winter Hairstyle 2012 - Hot Fall Winter Hairstyle Trends 2012
Winter Hairstyle 2012 - Hot Fall Winter Hairstyle Trends 2012
Hairstyles How to choose a winter hairstyle
If you are looking for a Winter hairstyle trends it starts with all about angles, edges, cuts and feminine designs,from pretty pixies to sassy spikes, gamine glam, polished chic and the layered look for sliced, subtle,tapered and choppy haircuts give women the option of having face framing or flippy looks to flared and wispy.
Latest trends for winter hairstyles includes bangs, layers, retros and bobs:
Fringe bangs will sharpen up any short cut add shine to a pin straight finish you can wear your fringe over one eye with a slight part on the opposite side and use a comb to smooth out the hair with a flat iron for a sleek look.
Bangs can be cut in various exciting new ways from ultra full, angled, curvy or cropped,
whatever your hair type from thin and fine, to curly and thick to straight and medium you can achieve a sexy look with rounded bangs or lash length tresses.
You can have a soft feminine tousled look for many head turning beach waves, retro waves or coils to flirty crowns that leave your hair longer on the top and tapered near the nape of the neck and ears.
Retro crop with a hollywood glam look can be achieved with classic curls, edgy waves or baby fine flair in a variety of haircolors from auburn to chocolate browns to fiery reds or platinum blondes.
Mid-length locks allow for a bold statement since big hair is what is in right now of full bodied curls for volume,
for straight face framing layers to a classic chic chin length blunt cut my favorite would be the asymmetric design because of its strong jagged layers and heavy bangs create a shape of drama and fashion style.
Don't forget to add your clip on accessories for vintage glam.
Adding body to the hair with a curling iron or flat iron is a way to get a dramatic effect. If you choose to dye your hair a bold color like blue or pink it will look cute to add hair extensions for length or volume.
Searching Tags for Winter Hairstyle 2012:-Winter Hairstyle 2012, autumn winter hairstyle layers, winter hairstyles for 2012, winter hairstyles for long hair, best Winter Hairstyle 2012, cute winter hairstyles for long hair, cute winter hairstyles for girls, cute winter hairstyles for medium hair, cute winter hairstyles picture
Hairstyles How to choose a winter hairstyle
If you are looking for a Winter hairstyle trends it starts with all about angles, edges, cuts and feminine designs,from pretty pixies to sassy spikes, gamine glam, polished chic and the layered look for sliced, subtle,tapered and choppy haircuts give women the option of having face framing or flippy looks to flared and wispy.
Latest trends for winter hairstyles includes bangs, layers, retros and bobs:
Fringe bangs will sharpen up any short cut add shine to a pin straight finish you can wear your fringe over one eye with a slight part on the opposite side and use a comb to smooth out the hair with a flat iron for a sleek look.
Bangs can be cut in various exciting new ways from ultra full, angled, curvy or cropped,
whatever your hair type from thin and fine, to curly and thick to straight and medium you can achieve a sexy look with rounded bangs or lash length tresses.
You can have a soft feminine tousled look for many head turning beach waves, retro waves or coils to flirty crowns that leave your hair longer on the top and tapered near the nape of the neck and ears.
Retro crop with a hollywood glam look can be achieved with classic curls, edgy waves or baby fine flair in a variety of haircolors from auburn to chocolate browns to fiery reds or platinum blondes.
Mid-length locks allow for a bold statement since big hair is what is in right now of full bodied curls for volume,
for straight face framing layers to a classic chic chin length blunt cut my favorite would be the asymmetric design because of its strong jagged layers and heavy bangs create a shape of drama and fashion style.
Don't forget to add your clip on accessories for vintage glam.
Adding body to the hair with a curling iron or flat iron is a way to get a dramatic effect. If you choose to dye your hair a bold color like blue or pink it will look cute to add hair extensions for length or volume.
Searching Tags for Winter Hairstyle 2012:-Winter Hairstyle 2012, autumn winter hairstyle layers, winter hairstyles for 2012, winter hairstyles for long hair, best Winter Hairstyle 2012, cute winter hairstyles for long hair, cute winter hairstyles for girls, cute winter hairstyles for medium hair, cute winter hairstyles picture
Men HairStyle Tips 2012 - How To Spike Curly Hair For Men
Men HairStyle Tips 2012 - How To Spike Curly Hair For Men.
The spiked style of hair has increased in popularity as a favored hairstyle for men. This option is considered convenient in terms of maintenance among those with naturally straight strands but can be difficult to obtain for individuals with curlier locks. The following tips can provide a guide on how to spike curly hair and maintain this trendy look.
The process for a sleeker appeal begins with washing your tresses. Be sure to use shampoo and conditioner that are specifically designed for wavier strands in order to provide extra protection against drying out and styling damage. It is best advised to include lightweight products for improved manageability and flexibility where cleaner strands are also easier to style.
Products which do not contain creamy contents will give curlier tresses a lighter feel and provide straighter strands which will be easier to transform into spikes. Once you have completed the process of shampooing and conditioning, rinse and simply pat dry with a towel. Do not completely dry your locks at this point but keep the strands fairly moist for improved manageability.
Use a wide toothed comb or larger hairbrush to untangle the strands and remove any frizz from developing. Narrow toothed combs should not be used in thicker, wavier hair as it simply causes damage to the locks. Remember to only untangle longer tresses when you have added moisture to it as attempting to comb through thick and dry locks could prove to be difficult and cause considerable breakage.
While the strands are still moist apply a fair amount of gel or wax that is designed for thick and curlier tresses. Depending on the appearance you desire, remember that gel will give your locks a wet look whereas wax will provide a matte appearance. Only use very small amounts of product on the strands as too much gel or wax will contribute to a rigid appearance.
Ensure even coverage of product through your locks as this will further contribute to a more natural appeal even providing the hair with some body and movement. The spiking process can occur once the gel or wax has been distributed evenly and involves using your fingers to create smaller spikes. One may also use a wide toothed comb to brush the strands in an upward motion for short spikes which will also appear more natural.
If larger spiking options are desired, simply place a small strand in between the fingers and proceed to twirl each piece into the determined shape. One can also limit the number of spikes on the head by placing a fair amount in the front and leaving the lengthier back area smooth. The length and number of spikes that an individual desires is completely dependent on personal preference and style.
Once you have obtained the desired look, to remove excess moisture go over the tresses with a blow dryer. Be sure to adjust the hairdryer settings to a low heat and blowing option to allow the style to settle and then add a spray in order to keep the locks in place. The process of how to spike curly hair is simple for obtaining a trendy hairstyle for men.
Searching Tags for Men HairStyle Tips 2012:-
Men HairStyling Tips 2012, hairstyle tips, haircut tips, top hairstyle ideas for men, top haircut ideas for men, top celebrity hairstyles, top classic haircuts, men style, man’s style trends 2012, Spike Curly Hair For Men, hair growth, hair growth tips, hair regrowth, natural hair growth tips
The spiked style of hair has increased in popularity as a favored hairstyle for men. This option is considered convenient in terms of maintenance among those with naturally straight strands but can be difficult to obtain for individuals with curlier locks. The following tips can provide a guide on how to spike curly hair and maintain this trendy look.
The process for a sleeker appeal begins with washing your tresses. Be sure to use shampoo and conditioner that are specifically designed for wavier strands in order to provide extra protection against drying out and styling damage. It is best advised to include lightweight products for improved manageability and flexibility where cleaner strands are also easier to style.
Products which do not contain creamy contents will give curlier tresses a lighter feel and provide straighter strands which will be easier to transform into spikes. Once you have completed the process of shampooing and conditioning, rinse and simply pat dry with a towel. Do not completely dry your locks at this point but keep the strands fairly moist for improved manageability.
Use a wide toothed comb or larger hairbrush to untangle the strands and remove any frizz from developing. Narrow toothed combs should not be used in thicker, wavier hair as it simply causes damage to the locks. Remember to only untangle longer tresses when you have added moisture to it as attempting to comb through thick and dry locks could prove to be difficult and cause considerable breakage.
While the strands are still moist apply a fair amount of gel or wax that is designed for thick and curlier tresses. Depending on the appearance you desire, remember that gel will give your locks a wet look whereas wax will provide a matte appearance. Only use very small amounts of product on the strands as too much gel or wax will contribute to a rigid appearance.
Ensure even coverage of product through your locks as this will further contribute to a more natural appeal even providing the hair with some body and movement. The spiking process can occur once the gel or wax has been distributed evenly and involves using your fingers to create smaller spikes. One may also use a wide toothed comb to brush the strands in an upward motion for short spikes which will also appear more natural.
If larger spiking options are desired, simply place a small strand in between the fingers and proceed to twirl each piece into the determined shape. One can also limit the number of spikes on the head by placing a fair amount in the front and leaving the lengthier back area smooth. The length and number of spikes that an individual desires is completely dependent on personal preference and style.
Once you have obtained the desired look, to remove excess moisture go over the tresses with a blow dryer. Be sure to adjust the hairdryer settings to a low heat and blowing option to allow the style to settle and then add a spray in order to keep the locks in place. The process of how to spike curly hair is simple for obtaining a trendy hairstyle for men.
Searching Tags for Men HairStyle Tips 2012:-
Men HairStyling Tips 2012, hairstyle tips, haircut tips, top hairstyle ideas for men, top haircut ideas for men, top celebrity hairstyles, top classic haircuts, men style, man’s style trends 2012, Spike Curly Hair For Men, hair growth, hair growth tips, hair regrowth, natural hair growth tips
Christmas Wishes
The best of all gifts around any Christmas tree: the presence of a happy family all wrapped up in each other. ~Burton Hillis
Merry Christmas Eve friends. The big day is upon us, family will be arriving soon, time to take a rest and enjoy all my little blessings.
We decorated 2 trees this year, one for the children with all our collected ornaments, and one for me with all my decorative ornaments...I call it my bird tree as it somehow turned into that and this year the theme was the peacock. While Tory Burch as seen above and Mary McDonald have peacock tree decor I aspire to, my little colorful birds and colored ribbon will have to do this season.
From my home to yours, Merry Christmas, Happy Holiday!
Wednesday, December 21, 2011
Checking In
I can hardly believe Christmas and the New Year are upon us. Are you ready or possibly to the point where I am in throwing my hands in the air to surrender?
Sorry for the radio silence on the blog...I have taken a bit of an unintentional hiatus as you may have noticed but I have been lingering around in blog land, not totally absent, just too caught up with life to post something of my own.
While I was away my business has grown, (hence no posting) and I couldn't be more excited! I have amazing clients and have added some fun ones to the mix, 2012 is looking good. With that in mind, I am putting out feelers for a young intern starting in January. If you or anyone you know night be interested message me, let's chat.
It would be next to impossible to catch you up on all the goings on of the last month and believe me there are some stories to tell... promise to post in a more timely manner, no excuses
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